Applications of the Sodium Fluorescein technique

FLUORESCENCE PHOTOGRAPHY

Application	Notes	Reference
Scabies	Painted the skin surface with fluorescein then washed the skin. The burrows were clearly revealed by the fluorescein solution. Recommended as an aid in identifying infected areas.	Hirschfeld 1946
Gall bladder surgery	Found fluorescein most useful in clearly delineating the extra-hepatic ducts and as a liver function test but not useful for visualisation of the ureters.	Menaker & Parker 1950
Upper GI haemorrhage	Fluorescein used to detect upper gastro-intestinal bleeding.	Traphagen 1958
Upper GI haemorrhage	Localisation of the haemorrhage is accurately determined by fluorescent examination of ingested, specially prepared string following injection of fluorescein. Gives proof and location of bleeding in gastro-intestinal tract.	Haynes & Pitman 1960
Paget's disease of Vulva	Visualisation and assessment in surgical management of Paget's disease of the vulva.	Misas et al. 1991
Gastro-intestinal haemorrhage	Localisation of the haemorrhage using the fluorescein string test.	Berk et al. 1962

Berk, J. & Kantor, S., 1962, "Demethylchlortetracylcine--induced fluorescence of gastric sediment," JAMA179 (13):152- 155.
Haynes, W. and Pittman, F., 1960, "Application of the fluorescein string test in 32 cases of upper gastrointestinal haemorrhage," Gastroent. 38 (6):690- 697.
Hirschfeld, R., 1946, "A contribution to the use of the Wood's light in dermatology: Burrows of itch revealed by fluorescence," Acta Dermat. Venereol. 26:471-475.
Menaker, G. and Parker, M., 1950, "Fluorescein: an adjunct in surgery of the gall bladder and biliary passages," Surg. 27:41-48.
Misas, J., Cold, C. and Hal, F., 1977, "Vulvar Paget Disease: Fluorescein-aided visualization of margins" Obstet Gynaecol : 77(1):156-159.
Traphagen, D. and Karlan, M., 1958, "Fluorescein string test for localization of upper gastro-intestinal hemorrhage" Surg. 44 (4):644-645.